The Hong Kong Society of Dermatology & Venereology Annual

نویسنده

  • WF Wu
چکیده

A number of important, interesting articles pertaining to paediatric dermatology were published in 2013 to 2014. Some of them were related to infections; like swimmer’s nodules on limbs due to an outbreak of atypical mycobacterial infection in school swimming pools. The risk factors include atopy and immunocompromised state. Other topics included (1) a winter outbreak of atypical hand, foot and mouth disease caused by Coxsackie A6 virus in Western countries, with a more severe presentation of fever, illness, large blisters and post-illness onychomadesis; (2) staphylococcal scalded skin syndrome not caused by methicillinresistant Staphylococcus aureus (MRSA) which has a high rate of clindamycin resistance and therefore both oxacillin and clindamycin were suggested as treatment. Genetic dermatology was also discussed with examples of RASA-1 gene mutation related capi l lary mal format ion-ar ter iovascu lar malformation (CM-AVM) syndrome and ParkesWeber syndrome. Capillary malformationarteriovascular malformation presents with small 1 to 3 cm macules surrounded by blanched halos and could be associated with intracranial AVM. HRAS and KRAS gene mutations were also found in various naevi like naevus sebaceous, epidermal naevus and naevus spilus. RAS mutations were also found to be associated with raised FGF23 levels leading to hypophosphataemia-related rickets.

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تاریخ انتشار 2014